The animal facility is one of Ci2A’s headliner facilities, with an area of ​​approximately 4,500 m2 and a capacity for 35,000 cages.

This service is in charge of the study of behaviour in experimental animals and in animal models that reproduce pathological or clinical symptoms of human diseases, with special emphasis on brain diseases and ageing.

This service has the necessary advanced equipment for high-resolution optical and confocal microscopy (nanoscopy) of samples that are fixed and/or maintained ex vivo.

This service facilitates real-time study for the functional activity of genetically identified cell populations and neuronal circuits involved in specific behavioural processes and their alteration in neurodegenerative and pathological processes.

This service carries out Nuclear Medicine studies on in vivo experimental animals. It is intended to combine the use of functional and structural imaging with the production of probes from their chemical precursors for multimodal imaging.

This service consists of two large rooms located on the first and second floors of the building. The rooms are used for the production and maintenance of primary cultures of neurons and glial cells and organotypic cultures of brain slices, as well as human induced pluripotent stem cells (iPSC), cell lines of human origin and organoid cultures.

This service supports researchers in the design of assays, sample analysis, and presentation of results in the field of flow cytometry. Among its main functions, it is in charge of developing flow cytometry protocols adapted to specific problems based on the nature and dynamics of the sample.

This service provides extensive coverage for researchers, advising on all basic molecular biology techniques, including WB, quantitative PCR, RNAscope, nucleic acid extraction, and generation of DNA and RNA libraries.

Omic technologies are high-resolution technologies that are applied today, mainly in basic and clinical research (for example, cell and tissue transcriptomics, proteomics and lipidomics).

The analysis of the omic data are carried out in the bioinformatics service and includes primary analysis, together with the preparation of FASTQ files, Excel files with quantification and advanced statistical analysis, heat-map representations, description of protein functions, and the genes (Gene Ontology) of the pathways involved (interactomes, SYNGO, Ingenuity and KEGG pathway analyses).

Nuclear Magnetic Resonance (NMR) is the most widely used spectroscopic technique in the field of Organic Chemistry.

The purpose of the microanalysis service is to determine the elements C, H, N and S by means of elemental analysis by combustion.

The objective of this Service is the biophysical characterization of the final products prepared within the Institute.

This is an area destined for the preparation of biological samples that includes equipment for the expression and purification of proteins.

The main objective of this service is the manufacture and fine-tuning of custom-made scientific equipment to facilitate research work via the design, development and production of the tools for the centres served by the Ci2A.

Due to the great technological advances that are emerging in the field of neurosciences and chemical sciences, we understand that research in the field is constantly changing, opening pathways to new studies and the incorporation of new tools.

Check out the International Project Management service and General Support Services at the Ci2A centre.